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Is with intravenous antibiotics such as vancomycin. An oral drug which can be safely administered for an extended period of time could improve care and standard of living for these patients.. Cempra commences CEM-102 Stage 2 trial in prosthetic joint infections Cempra, Inc. , a clinical-stage pharmaceutical business centered on developing antibiotics to meet critical medical needs in the treating bacterial infectious diseases, today announced the initiation of its Phase 2 medical trial of CEM-102 in sufferers with prosthetic joint infections .S. Related StoriesAntibiotic resistance potentially threatens the basic safety and efficacy of surgical procedures and immunosuppression therapiesShared decision making between doctors and individuals useful in fight against antibiotic resistanceArchbishop of York agrees to be Antibiotic Research UK's Patron ‘The option of an all-oral antibiotic regimen for the treatment of PJI supplies the promise of practical medication administration without the expense and morbidity of keeping long term venous gain access to,’ said David Oldach, M.D., FIDSA, senior vice president of clinical study.’ Prabhavathi Fernandes, Ph.D., president and ceo of Cempra added, ‘Cempra's objective is to build up differentiated antibiotics for individuals with unmet needs.’ PJIs happen in about 1 percent of hip replacements and 2 percent of knee replacements, with a standard incidence rate of about 10,000 per year in the U.S.