Both European Commission and the U.S. Food and Medication Administration granted orphan-medication designation for BAX 111 in November 2010. Baxter intends to apply for approval in the usa before the last end of 2014 and, predicated on these total results, intends to pursue a report of BAX 111 in a prophylaxis treatment establishing prior to the end of the entire year.. Baxter reports topline outcomes from BAX 111 Stage 3 trial for treatment of von Willebrand disease Baxter International Inc. today announced topline outcomes from a Phase 3 medical trial evaluating the security, efficacy and pharmacokinetics of BAX 111. BAX 111 is normally a recombinant von Willebrand element under investigation for the treating bleeding episodes in individuals with von Willebrand disease, the most typical kind of inherited bleeding disorder.Dr. Zhang may be the 2015 recipient of the American Association of Anatomists C.J. Herrick Award in Neuroanatomy for his use the CRISPR-Cas9 genome manipulation technology. On Monday March 30th 2015, Dr. Zhang will business lead a lecture, Advancement and Applications of CRISPR-Cas9 for Genome Manipulations, at the AAA annual meeting at Experimental Biology 2015. Related StoriesApoE4-carrying men with Alzheimer's disease vulnerable to mind bleedsResearchers identify tumor suppressor genes that travel subset of melanomasStudy suggests potential new way to block cancer-leading to gene Among my long-term goals is to develop CRISPR-Cas9 as a therapeutic strategy, also to do that, we must focus on deploying and refining the technique in vivo first.