Appetite-Controlling Hormone Leaves Obese People Still Hungry Researchers statement that although glucagon loses it is ability to help obese people feel full after meals, it continues to suppress hunger pangs in people with type 1 diabetes. The team's findings shall be published in the Journal of Clinical Endocrinology & Metabolism. The primary part of glucagon, a hormone secreted by the pancreas, is to signal the physical body to release stored glucose when bloodstream sugar falls too low mildronate-meldonium.com . But growing evidence suggests the hormone also may play a role in controlling diet and feelings of fullness through signaling the body to reduce degrees of additional appetite hormones like ghrelin. Once a person becomes obese, glucagon no induces feelings of fullness, explained the scholarly research;s lead writer, Ayman M.