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Both AN2728 and AN2898 have demonstrated efficacy in human clinical trials of psoriasis, said David Perry, Chief Executive Officer of Anacor Pharmaceuticals. Pre-clinical studies suggest that they may also succeed in dealing with atopic dermatitis. This trial is supposed to understand the potential of every substance to treat the condition, and, if effective, determine which compound to progress in development further. .. Anacor Pharmaceuticals initiates AN2728, AN2898 Phase 2 trial in mild-to-moderate atopic dermatitis Anacor Pharmaceuticals announced today that the 1st patient has been dosed in a Stage 2 trial of AN2728 and AN2898 to determine safety, tolerability and efficacy of the two compounds for the topical treatment of mild-to-moderate atopic dermatitis. The Phase 2 trial is a six-week, double-blind, randomized, bilateral trial evaluating each item candidate against its vehicle in 60 to 80 adults with mild-to-moderate atopic dermatitis.